The Sansoz Research Laboratory conducts fundamental research to understand the mechanics and physics of deformation and failure in nanostructured materials at the smallest scales. Through in-situ electron microscopy experiments, state-of-the-art atomistic simulation, and materials theory, we aim to push the scientific frontiers of mechanical, thermal, and electrical properties of nanomaterials. These discoveries are of paramount importance, as they pave the way for advanced engineering applications in extreme environments, spanning across energy, aerospace, electronics, and modern computing.