{"id":735,"date":"2021-12-10T16:46:16","date_gmt":"2021-12-10T16:46:16","guid":{"rendered":"https:\/\/site.uvm.edu\/cals-news\/?p=735"},"modified":"2021-12-13T14:20:33","modified_gmt":"2021-12-13T14:20:33","slug":"mckay-epigenome-research","status":"publish","type":"post","link":"https:\/\/site.uvm.edu\/cals-news\/mckay-epigenome-research\/","title":{"rendered":"McKay Funded for Cattle and Sheep Pan-Epigenome Research"},"content":{"rendered":"
\"A
Photo credit: Shelburne Farms<\/figcaption><\/figure>\n

Establishing a Pan-Epigenome for Cattle and Sheep is a newly funded $1.3 million dollar USDA NIFA grant that is being led by Animal & Veterinary Sciences Associate Professor Stephanie McKay<\/a>, in collaboration with Darren Hagen, PhD, at Oklahoma State University, and Brenda Murdoch, PhD, at the University of Idaho.<\/p>\n

This project encompasses comprehensive characterization of conservation and diversity of both cattle and sheep epigenomes. So, what is the epigenome? The epigenome includes chemical modifications, like adding methyl groups also known as methylation, to histones, DNA and RNA bases through the genomes of each animal, and influences gene function and subsequently affects economically important traits in livestock species. These chemical modifications to the genetic codes of individuals can be influenced by the environment and can be passed on from one generation to the next.<\/p>\n

In this project, the amount and location of methylation on DNA and RNA, and histones as well as other chemical modifications, of three primary tissues for multiple breeds of cattle and sheep will be characterized. Cataloging epigenetic diversity across cattle and sheep will increase our understanding of how different genomes, epigenomes, and gene products from diverse breeds of cattle and sheep will affect a variety of important biological traits, and support more accurate prediction of these traits for improved breeding strategies.<\/p>\n","protected":false},"excerpt":{"rendered":"

Establishing a Pan-Epigenome for Cattle and Sheep is a newly funded $1.3 million dollar USDA NIFA grant that is being led by Animal & Veterinary Sciences Associate Professor Stephanie McKay, in collaboration with Darren Hagen, PhD, at Oklahoma State University, and Brenda Murdoch, PhD, at the University of Idaho.<\/p>\n","protected":false},"author":7974,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[12,28,57,14],"tags":[16],"class_list":["post-735","post","type-post","status-publish","format-standard","hentry","category-cals","category-faculty","category-grants","category-research","tag-asci"],"jetpack_featured_media_url":"","jetpack-related-posts":[{"id":2448,"url":"https:\/\/site.uvm.edu\/cals-news\/cals-at-the-plant-and-animal-genome-conference\/","url_meta":{"origin":735,"position":0},"title":"CALS at the Plant and Animal Genome Conference","author":"CALS Communications","date":"January 25, 2023","format":false,"excerpt":"Several CALS faculty and graduate students presented research at the annual Plant and Animal Genome Conference (PAG 30), held January 13-18 in San Diego, CA. In his talk, But Does it Taste Good? A DIVSEEK thematic hub on crop germplasm uses, Eric Bishop von Wettberg, associate professor in the Dept.\u2026","rel":"","context":"In "Awards"","block_context":{"text":"Awards","link":"https:\/\/site.uvm.edu\/cals-news\/category\/awards\/"},"img":{"alt_text":"four CALS researchers posing for the camera outside at an academic conference.","src":"https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2023\/01\/PAG-1_800x400.jpeg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2023\/01\/PAG-1_800x400.jpeg?resize=350%2C200 1x, https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2023\/01\/PAG-1_800x400.jpeg?resize=525%2C300 1.5x, https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2023\/01\/PAG-1_800x400.jpeg?resize=700%2C400 2x"},"classes":[]},{"id":287,"url":"https:\/\/site.uvm.edu\/cals-news\/mckay-cattle-genomics\/","url_meta":{"origin":735,"position":1},"title":"McKay Leads New Cattle Genomics Collaboration","author":"CALS Communications","date":"September 21, 2021","format":false,"excerpt":"A team of researchers from four universities across the U.S. was awarded an Agricultural Genome to Phenome Initiative (AG2PI) grant to establish the \"Cattle Genome to Herd Phenotyping for Precision Ag\" initiative. UVM Animal and Veterinary Sciences Department Associate Professor Stephanie McKay is the lead principal investigator for the project,\u2026","rel":"","context":"In "CALS"","block_context":{"text":"CALS","link":"https:\/\/site.uvm.edu\/cals-news\/category\/cals\/"},"img":{"alt_text":"Holstein dairy cows in a barn.","src":"https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2021\/09\/mckay-dairy-cows.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2021\/09\/mckay-dairy-cows.jpg?resize=350%2C200 1x, https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2021\/09\/mckay-dairy-cows.jpg?resize=525%2C300 1.5x, https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2021\/09\/mckay-dairy-cows.jpg?resize=700%2C400 2x, https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2021\/09\/mckay-dairy-cows.jpg?resize=1050%2C600 3x"},"classes":[]},{"id":3328,"url":"https:\/\/site.uvm.edu\/cals-news\/cals-new-hires-august-2023\/","url_meta":{"origin":735,"position":2},"title":"CALS New Hires-August 2023","author":"CALS Communications","date":"August 30, 2023","format":false,"excerpt":"Trishnee Bhurosy, Assistant Professor, Department of Nutrition and Food Sciences Trishnee Bhurosy is a behavioral scientist with a research focus on improving nutrition equity and food security. She is addressing the behavioral and social determinants of nutrition behaviors underlying chronic conditions such as cancer. Bhurosy has specific interests in better\u2026","rel":"","context":"In "CALS"","block_context":{"text":"CALS","link":"https:\/\/site.uvm.edu\/cals-news\/category\/cals\/"},"img":{"alt_text":"Trishnee Bhurosy","src":"https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2023\/08\/Trishnee-Bhurosy.jpg?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":1307,"url":"https:\/\/site.uvm.edu\/cals-news\/animal-biosciences-phd-fellowships\/","url_meta":{"origin":735,"position":3},"title":"Animal Biosciences PhD Students Awarded Pre-doctoral Fellowships","author":"CALS Communications","date":"March 30, 2022","format":false,"excerpt":"Caitlin Jeffrey and Victoria Taormina, Ph.D. students in the Department of Animal and Veterinary Sciences (ASCI) Animal Biosciences program, received pre-doctoral fellowship grants under the USDA Agriculture and Food Research Initiative (AFRI) Competitive Grants Program. The fellowships from the Education and Workforce Development Program provide two years of salary, tuition\u2026","rel":"","context":"In "Awards"","block_context":{"text":"Awards","link":"https:\/\/site.uvm.edu\/cals-news\/category\/awards\/"},"img":{"alt_text":"Dairy cows in a lightly snow covered field in late fall.","src":"https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2022\/03\/dairy-cows-pastured.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2022\/03\/dairy-cows-pastured.jpg?resize=350%2C200 1x, https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2022\/03\/dairy-cows-pastured.jpg?resize=525%2C300 1.5x, https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2022\/03\/dairy-cows-pastured.jpg?resize=700%2C400 2x, https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2022\/03\/dairy-cows-pastured.jpg?resize=1050%2C600 3x"},"classes":[]},{"id":2747,"url":"https:\/\/site.uvm.edu\/cals-news\/cals-new-hires-march-2023\/","url_meta":{"origin":735,"position":4},"title":"CALS New Hires-March 2023","author":"CALS Communications","date":"March 30, 2023","format":false,"excerpt":"Joao Costa, Associate Professor, Department of Animal and Veterinary Sciences Costa comes from the University of Kentucky in Lexington, where he was an assistant professor in the Department of Animal and Food Science. His expertise is in precision dairy and dairy cattle management as related to behavior, nutrition, One Health,\u2026","rel":"","context":"In "CALS"","block_context":{"text":"CALS","link":"https:\/\/site.uvm.edu\/cals-news\/category\/cals\/"},"img":{"alt_text":"Joao Costa","src":"https:\/\/i0.wp.com\/site.uvm.edu\/cals-news\/files\/2023\/03\/Joao-Costa.jpg?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":3912,"url":"https:\/\/site.uvm.edu\/cals-news\/barlow-spotlight-antimicrobial-resistance-research\/","url_meta":{"origin":735,"position":5},"title":"Barlow Recognized for Antimicrobial Resistance Research","author":"CALS Communications","date":"December 19, 2023","format":false,"excerpt":"https:\/\/youtu.be\/KU5uMeNNbkk?si=0eQcFU5Lwi9bH4ZD NIAMRRE, the National Institute of Antimicrobial Resistance Research and Education, gave the member spotlight to Animal and Veterinary Sciences Associate Professor John Barlow for November 2023. 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